Banks in Desoto County, Mississippi
64 active bank branches operated by 22 institutions, per FDIC records.
Active branches
64
Banks present
22
Deposits (2026)
$4.5B
Closings since 2020
11
9 openings
Largest banks by deposits in Desoto County (2026)
| Bank | Deposits | Share | Branches |
|---|---|---|---|
| Huntington Bank | $1.1B | 24.4% | 10 |
| Renasant Bank | $640M | 14.1% | 6 |
| Regions Bank | $456M | 10% | 4 |
| First Horizon Bank | $401M | 8.8% | 3 |
| BankPlus | $395M | 8.7% | 4 |
| Trustmark Bank | $283M | 6.2% | 5 |
| Guaranty Bank and Trust Company | $217M | 4.8% | 4 |
| Community Bank of Mississippi | $198M | 4.3% | 3 |
| First Security Bank | $181M | 4% | 4 |
| Wells Fargo | $136M | 3% | 1 |
Deposit location reflects the office to which deposits are reported and may not represent the residence of depositors.
Cities and towns
Transcribed from FDIC BankFind Suite active-location records and the annual Summary of Deposits. County assignment follows the FDIC branch record.