Banks in St. Louis County, Missouri
308 active bank branches operated by 58 institutions, per FDIC records.
Active branches
308
Banks present
58
Deposits (2026)
$48.5B
Closings since 2020
72
40 openings
Largest banks by deposits in St. Louis County (2026)
| Bank | Deposits | Share | Branches |
|---|---|---|---|
| Commerce Bank | $6.0B | 12.4% | 22 |
| Bank of America | $6.0B | 12.4% | 19 |
| U.S. Bank | $5.9B | 12.2% | 31 |
| Enterprise Bank & Trust | $4.4B | 9.2% | 7 |
| Regions Bank | $2.9B | 5.9% | 22 |
| PNC Bank | $2.7B | 5.5% | 14 |
| First Bank | $2.3B | 4.7% | 17 |
| Midwest BankCentre | $1.8B | 3.7% | 9 |
| The Central Trust Bank | $1.5B | 3.1% | 10 |
| Cass Commercial Bank | $1.1B | 2.2% | 2 |
Deposit location reflects the office to which deposits are reported and may not represent the residence of depositors.
Cities and towns
- Saint Louis (96)
- Chesterfield (25)
- Clayton (21)
- Florissant (16)
- Des Peres (12)
- Creve Coeur (12)
- Ballwin (10)
- Kirkwood (10)
- Ellisville (9)
- Fenton (9)
- Eureka (9)
- St. Louis (8)
- Webster Groves (7)
- Bridgeton (5)
- Affton (4)
- Manchester (4)
- Hazelwood (4)
- Town and Country (4)
- Brentwood (4)
- Jennings (4)
- Valley Park (3)
- Maryland Heights (3)
- Richmond Heights (3)
- Frontenac (3)
- Saint Ann (2)
- Glendale (2)
- Sunset Hills (2)
- Ferguson (2)
- Grover (2)
- University City (2)
- Olivette (1)
- Ladue (1)
- Crestwood (1)
- Mehlville (1)
- Shrewsbury (1)
- Overland (1)
- Maplewood (1)
- Dellwood (1)
- Wildwood (1)
- Lemay (1)
- Earth City (1)
Transcribed from FDIC BankFind Suite active-location records and the annual Summary of Deposits. County assignment follows the FDIC branch record.