Banks in Jefferson County, Missouri
44 active bank branches operated by 24 institutions, per FDIC records.
Active branches
44
Banks present
24
Deposits (2026)
$3.9B
Closings since 2020
4
5 openings
Largest banks by deposits in Jefferson County (2026)
| Bank | Deposits | Share | Branches |
|---|---|---|---|
| Enterprise Bank & Trust | $494M | 12.7% | 6 |
| First State Community Bank | $468M | 12% | 6 |
| U.S. Bank | $448M | 11.5% | 3 |
| Midwest BankCentre | $392M | 10.1% | 4 |
| Commerce Bank | $391M | 10.1% | 2 |
| Midwest Regional Bank | $385M | 9.9% | 2 |
| Carrollton Bank | $196M | 5% | 1 |
| Bank of America | $155M | 4% | 1 |
| Bloomsdale Bank | $134M | 3.4% | 3 |
| Southern Bank | $104M | 2.7% | 1 |
Deposit location reflects the office to which deposits are reported and may not represent the residence of depositors.
Cities and towns
Transcribed from FDIC BankFind Suite active-location records and the annual Summary of Deposits. County assignment follows the FDIC branch record.