Banks in Cape Girardeau County, Missouri
36 active bank branches operated by 16 institutions, per FDIC records.
Active branches
36
Banks present
16
Deposits (2026)
$3.5B
Closings since 2020
5
3 openings
Largest banks by deposits in Cape Girardeau County (2026)
| Bank | Deposits | Share | Branches |
|---|---|---|---|
| The Bank of Missouri | $490M | 14.1% | 5 |
| Wood & Huston Bank | $396M | 11.4% | 2 |
| Montgomery Bank | $349M | 10% | 3 |
| First State Community Bank | $260M | 7.5% | 3 |
| U.S. Bank | $251M | 7.2% | 3 |
| Banterra Bank | $246M | 7.1% | 1 |
| Southern Bank | $236M | 6.8% | 3 |
| Commerce Bank | $219M | 6.3% | 2 |
| Alliance Bank | $192M | 5.5% | 2 |
| Fm Bank And Trust | $191M | 5.5% | 3 |
Deposit location reflects the office to which deposits are reported and may not represent the residence of depositors.
Cities and towns
Transcribed from FDIC BankFind Suite active-location records and the annual Summary of Deposits. County assignment follows the FDIC branch record.